Company also Expands ionKey/MS System to SYNAPT and Xevo
Time-of-Flight Mass Spectrometers with New UPLC-Grade iKey Chemistries
BALTIMORE--(BUSINESS WIRE)--Jun. 16, 2014--
Waters Corporation (NYSE:WAT) today introduced two new Xevo®
mass spectrometers and expanded the ionKey/MS System at the 62nd
conference of the American
Society of Mass Spectrometry (ASMS). The Waters®
Xevo G2-XS mass spectrometer, a new high performance benchtop
quadrupole time-of-flight (QTofTM) mass spectrometer, and the Xevo
TQ-S micro, a new and compact benchtop tandem quadrupole mass
spectrometer, take benchtop quantitative and qualitative applications to
new levels.
Waters New Xevo® G2-XS mass spectrometer, a new high performance benchtop quadrupole time-of-flight (QTof) mass spectrometer, unveiled at the 62nd conference of the American Society of Mass Spectrometry. (Photo: Business Wire)
Waters also announced the expansion of the ionKey/MS™
System to the SYNAPT®
G2-S, SYNAPT G2-Si, Xevo G2-S QTof and the
newly-introduced Xevo G2-XS QTof micro mass spectrometer with new UPLC®
grade iKeyTM chemistries.
Additionally, Waters unveiled Progenesis®
QI for proteomics Version 2.0, the latest advance in proteomics data
analysis software, availability of Omics LLC’s PetroOrg Petroleomics
Software on the SYNAPT
G2-Si for chemical composition characterization of petroleum
and the exclusive rights to Prosolia's DESI (Desorption Electrospray
Ionization) technology for clinical research applications for use with
Waters' time-of-flight mass spectrometers.
Xevo G2-XS QTof Mass Spectrometer
Featuring the new XS Collision Cell, the Xevo® G2-XS mass
spectrometer stands alone among its peers in offering uncompromised
analytical sensitivity and selectivity in a benchtop QTof mass
spectrometer. Shipment of Xevo G2-XS QTof to customer laboratories is
expected to begin at the end of the second quarter with MassLynx®
software and in the fourth quarter under the UNIFI®
Scientific Information System.
“The technology embodied in the Xevo G2-XS benefits laboratory analysis
in a number of ways. Most importantly, laboratories now have a
dependable option for performing qualitative and quantitative
experiments for both known and unknown analytes with a benchtop QTof
instrument,” said Brian Smith, Vice President – Mass Spectrometry
Operations, Waters Division.
The Xevo G2-XS QTof mass spectrometer combines the new XS Collision Cell
with the proven, signature technologies of Tof-MRM, StepWaveTM
and QuanTofTM to deliver optimum levels of robust sensitivity
and selectivity, resulting in the detection of more low-level compounds
than ever before.
For targeted quantitative experiments, Tof-MRM mode delivers a 10-fold
improvement in signal-to-noise when compared to full scan mode,
resulting in limits of detection and quantification that completely
redefine expectations for a benchtop high resolution mass spectrometer.
Xevo TQ-S micro Mass Spectrometer
The Waters Xevo TQ-S micro is designed to acquire sensitive, robust and
dependable data at accelerated rates of acquisition for numerous
analytes at varying concentrations. Waters intends to commence shipments
of the Xevo TQ-S micro system in the third quarter.
“From a price to performance standpoint, the Xevo TQ-S micro is hard to
beat. When you add it all up, Xevo TQ-S micro is the smallest,
high-performance tandem quadrupole mass spectrometer on the market and
is a great new choice for scientists working in food, environmental,
pesticides, pharmaceutical bioanalysis and peptide screening,” said Gary
Harland, Director – MS Product Management, Waters Division.
Featuring new Xtended Dynamic Range™ technology, the Xevo TQ-S micro
mass spectrometer offers an impressive six orders of magnitude of linear
dynamic range. This is important for quantifying compounds in samples
where the concentrations of individual analytes differ greatly.
Furthermore, the wider the operational dynamic range, the easier it is
to transfer methods between instruments of differing sensitivities.
The Xevo TQ-S micro’s new Xcelerated Ion Transfer™ (XIT) electronics
allow the instrument to acquire as many as 500 MRMs/sec without
significantly reducing peak intensities, which no other tandem
quadrupole instrument currently offers. This performance boost means
that labs performing pesticide screening, drug, and peptide analyses can
monitor for a wider range of analytes than ever before.
Xevo TQ-S micro exceeds expectations for a mass spectrometer of its
compact size, offering significant enhancements in absolute sensitivity
and signal-to-noise over entry-level tandem quadrupole instruments.
Robustness testing has confirmed excellent reproducibility between many
repeat injections over an extended time period, which is particularly
important for laboratories that have built their reputation on fast
turnaround times and accuracy.
Expansion of ionKey/MS System
First unveiled in March 2014 for use with the ACQUITYUPLC® M-Class System
and XevoTQ-S Mass Spectrometer, the ionKey/MS
System is now available on the SYNAPT
G2-S, SYNAPT G2-Si, Xevo G2-S QTof and the newly introduced Xevo
G2-XS QTof mass spectrometer. The ionKey/MS expansion also includes new
iKey chemistries, specifically HSS
T3 (high strength silica) and BEH
C4 (Bridged Ethyl Hybrid) 1.7 micron UPLC grade particles
in five and ten centimeter pathlengths. When first introduced, the iKey
featured C18, BEH 300, Å CSH (Charged Surface Hybrid) and C18
BEH 130 Å chemistries.
The Waters ionKey/MS System physically integrates a UPLC separation into
the mass spectrometer producing a significant improvement in
sensitivity, enabling scientists to achieve unparalleled separation and
detection of compounds.
Early adopters of the ionKey/MS System are already reporting exceptional
sensitivity, robustness and ease-of-use out of mass spectrometry for
applications as far-ranging as bioanalyses and pharmacokinetic studies
to food safety and environmental analyses.
In addition to the enhanced sensitivity, scientists praise the plug and
play nature of ionKey/MS. Scientists no longer have to contend with
delicate fittings and columns and concern themselves with extra column
dispersion and the inevitable variability and band broadening that comes
with it.
Progenesis QI for Proteomics
The Progenesis
QI for proteomics Version 2.0 is the latest advance in proteomics
data analysis software enabling more rapid and reliable quantification
and identification of differentially changing proteins in laboratory
samples than ever before. The release of Progenesis QI for proteomics
Version 2.0 expands Waters’ suite of focused, world-leading informatics
packages for 'omics data analysis.
The new features of Progenesis QI for proteomics Version 2.0 include
Pathway Analysis, which aids the biological understanding of observed MS
data; QC Metrics, which assesses LC-MS data quality to facilitate
exclusion of sub-optimal measurements; and Process Automation, which
eliminates the need to program repetitive steps to make analysis even
faster. The new software now allows user-selectable HiN quantification
of proteins, along with full HiN functionality for 2D-LC experiments.
Progenesis QI for proteomics Version 2.0 takes ‘omics-based data
analysis to the next level by enabling users to rapidly quantify and
identify differences between protein samples. It provides an
easy-to-learn, intuitive process based on how researchers work, a
flexible workflow and a highly visual interface to give the user
confidence in their data.
PetroOrg Petroleomics Software
Now available for SYNAPT
G2-Si, Omics LLC’s PetroOrg Petroleomics Software delivers
time saving performance, enhanced results and comprehensive data for
chemical composition characterization of petroleum.
Energy companies seek better analytical methodologies to determine crude
oil’s economic value and the level of refining required to produce
high-value products. However, the complexity of crude oils offers a
significant challenge to analytical chemists. Processing, visualizing
and interpreting the information rich mass spectral data has
traditionally been a costly and time-consuming process.
Waters and Omics LLC now make it possible to effortlessly access and
correlate accurate mass and ion mobility information derived from the
Waters SYNAPT HDMS® for petroleum compounds. By bringing
together Waters unique ion mobility-high resolution mass spectrometry
platform with PetroOrg Petroleomics Software, analytical chemists can
easily and quickly classify petroleum samples by chemical composition.
For more information about the petroleomics sample analysis solution
from Waters and Omics LLC, please visit: www.waters.com/petroleomics
Exclusive Agreement for DESI Technology for Clinical MS Applications
Waters signed an agreement with Prosolia,
Inc. (Indianapolis, IN) for the exclusive rights to DESI
(Desorption Electrospray Ionization) technology for clinical research
applications for use with Waters time-of-flight mass spectrometers,
including its SYNAPT
G2 Si and Xevo
G2-XS QTof mass spectrometers.
When used for clinical research studies, DESI is a non-destructive means
by which researchers using mass spectrometry can determine, with
specificity and speed, the molecular distributions of drugs, lipids and
metabolites from human tissue samples. Otherwise known as in vitro
“tissue imaging”, it allows scientists to potentially distinguish
healthy tissue from diseased tissue.
“By combining Prosolia’s DESI with Waters' time-of-flight mass
spectrometers, we see the potential to advance clinical research in
meaningful ways,” said Dr. Rohit Khanna, Vice President of Worldwide
Marketing and Informatics for the Waters Division. “This agreement with
Prosolia is an important step in fulfilling our vision of improving
human health by partnering with the biomedical community to make
breakthrough scientific discoveries and translate them into healthcare
solutions.”
A bottleneck in life science research is the time and expertise required
for sample preparation. Tissue sample preparation can be a tedious
process that often involves multiple steps, delaying the time to a
result, decreasing productivity and increasing the probability for
error. DESI eliminates this bottleneck by enabling direct, automated
analysis of tissue samples thereby reducing the requirement for
extensive sample preparation and enabling high throughput sample
analysis. These capabilities translate into lower laboratory operational
costs, streamlined workflows and faster results than traditional
approaches.
“Waters is a natural choice for Prosolia to partner with to advance the
DESI technology in the clinical research space,” said Dr. Justin
Wiseman, Chairman, President & CEO of Prosolia. “Waters’ mass
spectrometry technology and vision of a healthier future for humanity
appealed to us on many levels and we are looking forward to a long and
successful relationship.”
About Waters Corporation (www.waters.com)
For more than 50 years, Waters Corporation has created business
advantages for laboratory-dependent organizations by delivering
practical and sustainable innovation to enable significant advancements
in such areas as healthcare delivery, environmental management, food
safety, and water quality, consumer products and high-value added
chemicals worldwide.
Pioneering a connected portfolio of separations science, laboratory
information management, mass spectrometry and thermal analysis, Waters
technology breakthroughs and laboratory solutions provide an enduring
platform for customer success.
With revenue of $1.9 billion in 2013, Waters is driving scientific
discovery and operational excellence for customers worldwide.
Waters, SYNAPT, Xevo, MassLynx, UPC2, UPLC, ACQUITY, UNIFI,
ACQUITY UPLC, StepWave, ZSpray, Xtended Dynamic Range, Xcelerated Ion
Transfer, ionKey/MS, HDMS and Progenesis are trademarks of Waters
Corporation.
Prosolia is a trademark of Prosolia, Inc.
Photos/Multimedia Gallery Available: http://www.businesswire.com/multimedia/home/20140616005646/en/
Source: Waters Corporation
Waters Corporation
Brian J. Murphy, +1 508-482-2614
Public
Relations Manager
brian_j_murphy@waters.com