MILFORD, Mass.--(BUSINESS WIRE)--Jan. 30, 2018--
Waters Corporation (NYSE:WAT) today introduced the Waters®
ACQUITY™ Arc™ Bio System, a versatile, iron-free,
bio-inert, quaternary liquid chromatograph specifically engineered to
enable the efficient transfer and improvement of bioseparation
analytical methods regardless of the LC platform on which the original
method was developed.
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The Waters ACQUITY Arc Bio System is an iron-free, bio-inert, quaternary liquid chromatograph specifically engineered to enable the efficient transfer and improvement of bioseparation analytical methods regardless of the LC platform on which the original method was developed. (Photo: Business Wire)
Since its 2015 launch, the original ACQUITY
Arc System has become a workhorse of pharmaceutical development and
QC laboratories throughout the world. With the introduction of the
ACQUITY Arc Bio System, biopharmaceutical laboratories can take
advantage of the power of the ACQUITY Arc™ platform for creating robust
and reliable methods that can be transferred easily from lab-to-lab and
from one LC instrument platform to another without compromising method
integrity.
“For many GLP/GMP laboratories, developing and transferring validated
assays for routine product release and multi-attribute monitoring is a
fundamental task which Waters is committed to simplifying with the Arc
Bio System,” said Dr. Diane Diehl, Senior Director, Pharmaceutical
Market Development. “With today’s introduction, and yesterday’s launch
of the BioResolve
RP mAb Columns, Waters is continuing its commitment to the
biopharmaceutical industry by meeting the needs of analytical scientists
and lab managers across the discovery, development and manufacturing
pipeline.”
The ACQUITY Arc Bio System is ideally suited to run reversed-phase, ion
exchange, size exclusion and hydrophobic interaction LC methods with
minimal carryover and maximum recovery of biomolecules. The ACQUITY Arc
Bio System’s flow paths are made of non-stainless steel and iron-free
bio-inert materials designed to minimize undesirable protein
interactions and maximize system robustness under salt and pH extremes.
What also sets the instrument apart is the unique Arc Multi-flow path™
technology which delivers plug-and-play compatibility with HPLC or UHPLC
methods through a selectable dwell volume, emulating the dwell volume of
the original instrument. This minimizes the time it takes laboratories
to redevelop methods from internal and external partners.
In addition to replicating established HPLC assays, the ACQUITY Arc Bio
System can improve the sensitivity, resolution and speed of
chromatography methods by leveraging more modern, more efficient 2.5 -
2.7 micron particle column technologies. These include the new Waters
BioResolve™ RP mAb Polyphenyl solid core Columns for the
reproducible analysis of intact or sub units of monoclonal antibodies
(mAbs) and antibody-drug conjugates (ADCs). The system also supports
previously developed “legacy” methods on traditional 3 - 5 micron HPLC
columns.
The ACQUITY Arc Bio System is compatible with numerous detectors from
Waters, including photodiode array, UV/Vis, fluorescence, refractive
index, evaporative light scattering and the ACQUITY
QDa™ mass detector. In addition, the ACQUITY Arc Bio System features
novel Auto
Blend Plus™ Technology that automatically blends up to four solvents
in any combination or proportion and allows the operator to program in
pH and ionic strength for ion-exchange or size exclusion-based methods,
or program in the organic solvent concentration and pH for
reversed-phase gradient separations. This significantly reduces human
error and the task of preparing buffered mobile phases manually. The
ACQUITY Arc Bio System is controlled through Waters
Empower™ 3 and MassLynx™
software.
The ACQUITY Arc Bio System is immediately available for purchase
worldwide.
For more information on Waters ACQUITY Arc Bio System: www.waters.com/arcbio
About Waters Corporation (www.waters.com)
Waters
Corporation (NYSE: WAT), the world's leading specialty measurement
company, has pioneered chromatography, mass spectrometry, and thermal
analysis innovations serving the life, materials, and food sciences for
nearly 60 years. With approximately 7,000 employees worldwide, Waters
operates directly in 31 countries, including 15 manufacturing
facilities, and with products available in more than 100 countries.
Waters, ACQUITY, ACQUITY Arc, Arc, Arc Multi-flow path, ACQUITY QDa,
Auto Blend Plus, Empower, MassLynx, BioResolve and UPLC are trademarks
of Waters Corporation.
View source version on businesswire.com: http://www.businesswire.com/news/home/20180130005282/en/
Source: Waters Corporation
Waters Corporation
Brian J. Murphy, +1 508-482-2614
Public
Relations
brian_j_murphy@waters.com