Creating Access to the Power and Potential of Mass Spectrometry for
More Laboratories
MILFORD, Mass.--(BUSINESS WIRE)--Jun. 1, 2018--
Waters (NYSE:WAT) is giving scientists attending ASMS 2018 a first look
at new mass spectrometry technologies developed to serve the
multi-faceted analytical requirements of food testing, university and
biomedical research laboratories. The new products include a gas
chromatography-mass spectrometry/mass spectrometry (GC-MS/MS) system for
food safety analyses and a direct-analysis mass spectrometry system for
rapid molecular fingerprinting of food commodities, ingredients and
processed products. The Waters mass spectrometry products will be on
display at the 66th Conference on Mass Spectrometry and
Allied Topics (ASMS),
June 3 – 7.
Food Safety Analysis – Waters® Xevo™ TQ-GC
System
At ASMS Waters will preview its new Xevo TQ-GC mass spectrometer,
GC-MS/MS system for food safety and quality laboratories. The system, to
be officially launched later in the year, allows laboratories to
consistently meet and exceed limits of detection when quantifying
pesticides residues and other contaminants in food using GC-MS/MS
methods set forth by worldwide regulatory agencies/authorities. Hundreds
of pesticides are in use throughout the world, and with other emerging
contaminants regularly coming to the attention of regulatory
authorities, laboratories need to be able to accurately detect and
quantify pesticides in a variety of food types and GC-MS/MS, along with
liquid chromatography-mass spectrometry (LC-MS), is the preferred
technique of choice for the majority of them.
Food Authenticity and Adulteration – DART QDa with LiveID System
The product of a collaboration between Waters and IonSense™,
Inc. (Saugus, Mass.) the Waters™
DART™ QDa™ with LiveID™ System is a direct analysis system for rapid
molecular fingerprinting of food commodities, ingredients and processed
products. It allows scientists to answer questions such as: Is the
sample I’m testing authentic? Has the composition of it changed? Is
sample quality good or bad? Featuring the LiveID
software platform, the instrument performs real-time sample
recognition and verifies sample authenticity or adulteration in seconds.
Direct Analysis in Real Time (DART) is a direct and rapid analysis
technique for various sample types with minimal sample preparation and
no requirement for a chromatographic separation. The Waters LiveID
software trains and validates multivariate statistical models using the
chemical profile obtained from the DART QDa analysis. The LiveID models
can be used to identify unknown samples, generating easy-to-interpret
results in near real time and a simple yes/no answer in seconds.
Educating Tomorrow’s Science Leaders – ACQUITY QDa Practical MS
Education Package
The ACQUITY™
QDa Practical MS Education Package, developed jointly with the National
Mass Spectrometry Facility at
Swansea
University
in the UK, was created to give university chemistry
departments an affordable means to enable undergraduates to access mass
spectrometry equipment during their degree schemes and educate them in
the fundamentals of mass spectrometry.
Today’s undergraduates can be at a disadvantage since many mass
spectrometers at universities are housed in core or specialized
facilities, and typically only available to principal investigators
(PIs) and their extended teams for use with specific research projects.
Rarely are undergraduate students given direct access to the
instruments; yet hands-on experience with mass spectrometry and
knowledge of the related fundamentals is a valuable asset to college
graduates entering today’s workforce.
The Practical MS Education Package comes with everything needed to
introduce undergraduates to mass spectrometry including experiments,
student and instructor handbooks, instrumentation, software, chemistry
standards and multi-media content to enrich the teaching of mass
spectrometry fundamentals in the college classroom.
“The education package was developed, in partnership with Waters, to
give students an opportunity to have hands-on experience with mass
spectrometry and to learn to how to interpret spectra as part of an
analytical practical,” said Rhodri Owen, Experimental Officer, NMSF
Centre, Swansea University. “Being compact and quick to set up, the
ACQUITY QDa is ideal to move between labs and even off campus for
outreach events, and in 2017 we were able to give over 9,000 people a
chance to see it in action screening common household goods at the
Swansea Science Festival.”
Driving Biomedical Research
In other news, Waters and Elucidata
Corporation (Cambridge, Mass. and New Delhi, India) have entered into a
co-marketing agreement that combines the Waters
Symphony Data Pipeline™ Software with Elucidata’s
Polly™ Workflows and cloud applicationsto enable efficient
automated processing and interpretation of metabolic flux analysis
studies from Waters mass spectrometry data. Metabolomics flux studies
measure the production and consumption rates of metabolites in a
biological system.
Waters and Biognosys
AG (Schlieren, Switzerland) have expanded their marketing agreement to
include Biognosys® Spectronaut Pulsar® X software
and the PQ500 Reference peptide kit for the Waters Xevo G2-XS
QTOF quadrupole time-of-flight mass spectrometer running SONAR™
Software, a novel Data Independent Acquisition (DIA) technology. The
combined platform quantitates reproducibly a large number of proteins
(<500) in 15 minutes with single digit CVs. The platform is well-suited
for enabling biomedical research laboratories to rapidly characterize
and quantitate the protein profile of large sets of samples in a
systematic and standardized way for clinical proteomics research.
Also at ASMS, Waters announced the release of the Targeted Omics
Library, including the new MetaboQuan-R™
Method Packages. The Library is a growing repository of downloadable
Packages for rapidly expanding the number of analytes a lab can measure
while reducing method development time. Each Method Package includes a
Quanpedia™ file containing all chromatographic and mass spectrometric
settings for “load and go” use on the Waters ACQUITY
UPLC™ I-Class Plus System and Xevo
TQ-S micro triple quadrupole mass spectrometer and comes with an
application note for the associated method.
The latest version of Progenesis™
QI software for proteomics, which creates and queries spectral
libraries, is now capable of handling data dependent analysis (DDA)
data, supporting identifications from all the DDA search engines
supported by Progenesis QI for proteomics. It also incorporates a mass
spectrometry/mass spectrometry (MS/MS) spectral clean-up tool for
cleaner library matching. Progenesis QI for proteomics is an excellent
tool for performing host cell protein analysis, where the majority of
analytes can be found across multiple experiments. Additionally there is
an improved workflow for Waters MS(E) data with automatic peak detection
thresholding to maximize the number and quality of identifications,
while improving software performance.
Waters Announces Winner of This Year’s ASMS Research Award
This year’s recipient of an ASMS Research Award sponsored by Waters is Dr.
James Prell, Assistant Professor, Department of Chemistry and
Biochemistry, University of Oregon. The Prell laboratory uses
state-of-the-art mass spectrometry and ion mobility techniques to
investigate the physical and chemical properties that govern the
organization of macromolecular assemblies at the nanoscale, including
those found in biological membranes. Waters will present Dr. Prell his
award, and a check for $35,000, on Tuesday, June 5, at a presentation
beginning at 4:45 p.m. in Hall D of the Convention Center.
Waters scientists are giving a total of 12 oral and 76 poster
presentations at ASMS 2018. A complete list of them, including poster
#MP 034 titled Real-Time Authentication of Food and Beverages Using
DART QDa LiveID Analysis, is available at: www.waters.com/asms.
About Waters Corporation (www.waters.com)
Waters Corporation (NYSE: WAT), the world’s leading specialty
measurement company, has pioneered chromatography, mass spectrometry,
and thermal analysis innovations serving the life, materials, and food
sciences for nearly 60 years. With approximately 7,000 employees
worldwide, Waters operates directly in 31 countries, including 15
manufacturing facilities, and with products available in more than 100
countries.
Waters, ACQUITY, UPLC, Xevo, Symphony, SONAR, QDa, LiveID,
Quanpedia, and MetaboQuan-R are trademarks of Waters Corporation. DART
is a trademark of JEOL USA. IonSense is a trademark of IonSense, Inc.
Elucidata and Polly are trademarks of Elucidata Corporation. Biognosys
and Spectronaut Pulsar are trademarks of Biognosys.
View source version on businesswire.com: https://www.businesswire.com/news/home/20180601005264/en/
Source: Waters Corporation
Waters Corporation
Brian Murphy, 508-482-2614
Public Relations
Manager
brian_j_murphy@waters.com